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H1N1 "Swine" Flu

 

Nov 2, 2009

We are in this area seeing a decline in cases of Swine Flu.  I was seeing  20-30 cases a day and now it is 3-4 a day. 
The cases are on the upswing in other areas of America.

The deaths are continuing and mainly because there is such a huge number of cases. 
The number of deaths are not as many as 2008 regular flu cases.
 

Hopefully we will get the flu vaccine in ... supposed to be here any day... supposed to have been here
weeks ago. 

Dr. Knapp


Oct 26, 2009

There is a massive number of cases of Swine flu.  It is just now moving more up North.  We actually are over the hump here and are seeing a
decline in cases.  There now have been roughly 4 times as many cases of Swine flu as there are regular seasonal flu cases in the winter. 
In the 2007-2008 season there were 80 deaths  in children and 80 % of them had major health problems. 

The President announcing this as a National Emergency was a move designed to expedite disaster plans should hospitals get overwhelmed. 
There are approximately 4 times as many cases of swine flu, then we should see 320 deaths but there have been less. 
There were 67 deaths last winter from the regular flu.  There were 45 deaths from last Spring to Oct 09 from Swine flu.
There were 53 deaths since Oct 1 which is the beginning of the 2009-2010 season. That is a total of 98 deaths ... instead of 320. 

Remember the children who should get Tamiflu should have major health issues.... it is not just for everyone with the flu.
Also remember any fever after three days of flu cough and fever, we need to give them antibiotics for secondary pneumonia.

You can see how these cases and deaths stack up but not bad... see See: http://www.cdc.gov/flu/weekly/

We do not have H1N1 swine flu injectable vaccine and will post info at the flu clinic area when we do or sign up for Newsymail
and we will be sending out info.

Dr. Knapp


Oct 9, 2009

The news now has the report of the children dieing of the flu.  There are 2-3 times more cases of flu this year as apposed to
previous years.  See this graph from the CDC:

The first hump of cases to week 16 is our normal cases of flu.  As you can see there are many more cases
from week 16 to week 39.  There is normally only a very few cases or none after week 16. 
So with more cases then there will be more deaths ... tragically.  So if we look at this year's deaths to this week:

You can see there are more illnesses in the Spring, Summer and Fall when we normally do not see any. 
So if there are 2-3 times increase in flu cases,  then the deaths should be twice or more increase over
the normal number. That means 2 times 80 would give 160 to 240 cases.  But there has only been
76 tragic deaths from the H1N1 flu.   This new flu is just as dangerous as the old flu but there are
fewer deaths.  There are children and adults that die every year of the flu... the news media
usually does not mentioned them on the evening news.  That is why we have
a vaccine for Chicken Pox.  There were a few children who died of chicken pox every year and
you were never aware of them.  It was infrequent, tragic, but happened. 

I think we are over the peak of the cases of swine flu and should be on the down slope of cases (just when we
are about to get the vaccine!).  But then we will have the regular flu starting in December.

Dr. Knapp

p.s.  History note:  The Boy Scouts were to have their first National Jamboree in 1935.  Weeks before the event
they cancelled it even though preparations, tickets, posters and everything was all ready for the event.
They cancelled it because of the big outbreak of Polio that year and they did not want to spread it
with all the boys coming from all over America to one spot.  The first Jamboree was finally held in 1937.
Parents who are against all vaccinations like meningitis, polio, and other illnesses are idiots.


Oct 8, 2009  Well the CDC came out with recommendations for the new H1N1 vaccine that will be soon delivered.

They recommend that patients that had confirmed Swine H1N1 illness (that was documented by Reverse Transcriptase testing by the CDC which almost no one's virus was tested) do not have to receive the vaccine.  All others should get the vaccine .... even those that had tested positive for Type A flu by rapid testing in the doctor's office.  The test has many false negative tests and some false positive (meaning you don't have type A flu but test came out positive anyway.)

The number of false positives is very low.  And the Type A flu since last May have been 99.6 % H1N1 swine flu.  But because of the rare false positive, they want every one of those patients to get the shot just to be sure.  The illness stimulates very good immunity to this flu.  The regular seasonal flu will be coming in Dec-March and then it will be impossible to know if the illness is regular flu or swine flu if the test is pos for type A flu.

My personal opinion: 
1.  If you had a rapid test positive for Flu A then it was very likely you had the H1N1 swine flu.  I don't think you need the vaccine but it will not hurt you to get one if you so desire.
2.  If you had a negative test (which misses around 50% of the cases) but had "classic" symptoms, you probably do not need the vaccine but again it will not hurt you to get it if you so desire and want to be 100% sure.
3.  If you had a classic case of illness with 2-3 days of fever and were not tested for the flu, then you probably do not need the vaccine but again it will not hurt you to get the vaccine if you so desire.
4.  If you had a mild illness and really not classic flu symptoms, or did not get ill this Fall, then get the vaccine. (which is safe... see below.)

Dr. Knapp


Oct 7, 2009

This was an email I answered yesterday about the safety:

This is probably a question you are getting from so many, but what do you
really think about the H1N1 vaccine? I'm sure you've seen or heard
about the doctor on one of the news stations that's posted on youtube
saying that he thinks the vaccine is more dangerous than swine flu itself.

   That is crazy.  There was a problem with swine flu vaccine in the 1970s
   With a illness Guillian Barre.  The difference was so small in comparison
   to the general population  It occurs in normal people at 1/100,000.
   The vaccine in 1970s increased the chances so slightly that it then
   was 1 in a million chance of the vaccine causing this in patients.
   But 36,000 adults and 100 kids die every year from the flu.  Far better
   to get the vaccine.
  SEE: http://www.cdc.gov/h1n1flu/vaccination/gbs_qa.htm


What are the mercury levels like in the swine flu vaccine and
the regular flu vaccine? My 3 girls already got their shots at your
office for seasonal flu. Do you think there are risks with doing both?
Is the swine flu higher in mercury or any other preservatives that
might be dangerous than other vaccinations?


   The vaccines are safe.  The mercury does not cause health issues like
   Autism.  The amount of mercury is so miniscule that you get more mercury
   in the fish you eat.  And it is the Methyl mercury that hurts you from the fish.
   The Ethyl mercury in vaccines clears out of your body quickly.  They
   Have to put something in the vaccines to keep it sterile... either mercury or formaldehyde.
   But It is not enough to cause you any problems.
   See: http://www.myomancy.com/2005/05/ethyl_mercury_v


And, are you encouraging your grandchildren to be vaccinated against H1N1?

   Most definitely they will get it.

Dr. Knapp


Opinion Sept 5, 2009

 There are a lot more cases of flu this year which we expected since no one is immune to this.

 Many of the case deaths are from bacteria  and especially pneumonia after day 3.  So if your child has typical symptoms of flu (fever, headache, sore throat, mild cough, and pain in the windpipe with cough, and body aches) there is usually 3 days of fever, day 4 has fever of 100 and better, and day 5 has 99 fever and feels better still.  Any high fever 101 or more after day three, see the doctor or fill out the prescription of antibiotic that I gave you.  The children who have died of the flu are frequently kids with pneumonia after day 3.  That is what the 14 yr old who died of the flu in Fort Worth this last weekend.   She had fever Wed and Thur and Fri.  She saw the doctor Friday and he appropriately did not give Tamiflu.  But she started with high fever and lethargy day 4 on Sat and did not get care until Sunday.  So watch for fever after day three of the flu.  Tamiflu is for the high-risk kids; it only shortens fever one day; does not stop the shedding of the virus; and does not reduce the chances of secondary infections very much.  You still have to watch out for pneumonia. 
See: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm58e0929a1.htm?s_cid=rr58e0929a1_e

 

There is not an increase in deaths from the flu and pneumonia :

 

 See: http://www.cdc.gov/flu/weekly/

As you can see from these graphs, there are more visits with flu now but less mortality.  Hard to say why.  Maybe all the kids who were susceptible to dieing have already been exposed?  But there are more cases now.  The top graphs show the increase and WOW what a difference.  I have never seen this in the 30 yrs of practice.  This new strain is sweeping the world.  It is not more dangerous but there are a lot more cases.  And if you look at the middle graph above of deaths from flu and pneumonia, there is not an extreme increase.  The news again has you scared.   So watch for the fever after day 3 and get antibiotics quickly if that occurs. That has been true even years ago with the regular flu.  There have been deaths but the news did not broadcast it and you were not aware of them.

We do not know when we will get the swine flu vaccine in our office.  The news says we will get the nasal flu first but high risk cannot get that one.  So it looks like we will give the first vaccine to the low risk kids first.  ???? duh!.  The high risk groups will be getting the shot when it comes in.  I think most kids will have gotten this new flu before we give the vaccine.  I think it will be recommended for the high risk group first but it will be given to those who are in our office and ask for it.  So it will probably be first come first serve.  We are expected to get enough vaccine to give every one a vaccine for the swine flu.  But we will not have enough of the regular flu vaccine for the regular flu that comes in this winter.  Don't rush to get the regular flu vaccine since it does not show up until Dec thru March.  Hopefully will give both flu vaccines to your child at the same time in Nov. We can give both but we cannot give both nasal live vaccines at the same time.  We can give both injectable or one nasal and one injectable at the same visit.  We still do not know how many vaccines it will take.  Adults build up immunity with just one shot. We will see about the kids and ongoing studies are measuring it right now.

Dr. Knapp

 


Oct 1, 2009

There is a big shortage all over America of the regular flu vaccine.  We have sadly had to cancel clinics.  More vaccine will come later probably in November.  See the article:  http://www.google.com/hostednews/ap/article/ALeqM5jFXWlf10vStMfubD5l6VhQ1PxNGAD9B2H50O2
This is a great explanation of the shortage.

When we get the swine flu vaccine sometime this month (hopefully... ) and more of it in Nov. there is a recommendation to give it to high risk patients first.

So it looks like everyone will eventually get both vaccines but it may be last minute in Nov and Dec.
Dr. Knapp

(and we want government health care????  Yeow!)


Opinion Sept 27, 2009

Well another message about H1N1 swine flu.  We are continuing to be directed by the CDC to only treat high risk patients and not every one. 

 

We had a patient who had the swine flu and had a high risk person in the family.  By the time we diagnose the case, the high risk person (adult) was already exposed.  You are most contagious the day before fever.  And the medication Tamiflu does not stop the virus.  Studies showed that patients secrete the virus for up to 10-12 days with or without treatment.  The Tamiflu stops the symptoms sooner.  Some studies show less bacterial complications and some studies show no decrease in them with treatment.  So the adult in this case who is already exposed to the virus needs to consider Tamiflu and we did not treat the child who was doing well with the illness.  

SEE: http://www.usatoday.com/news/health/2009-09-14-H1N1-swine-flu_N.htm

 

The liquid medication of Tamiflu can be confusing.  It is 12mg/ml.  The eye dropper measures the medication in MG and not ml (volume).  So read the directions carefully.  Also the liquid is almost impossible to find.  I have been giving the pills and have them made into a liquid by the pharmacy or crush them up into food.

SEE: http://www.webmd.com/cold-and-flu/news/20090925/tamiflu-for-kids-confusing-dosage-can-harm

 

There is a huge increase of Swine flu.   I am seeing 20+ cases a day.  I am not testing  many of them since if it looks exactly like it, because the test does not help since the test misses half of the cases.  Whether it is pos or neg ... it is still H1N1.  Many physicians also do that.  So many cases are not reported.  We classify them as ILI (influenza like illness).  See these two graphs as an example.  First one is the reported cases but the second one is absentees from ILI.  Big increase.  Many schools have 100s of kids out.  There are far more cases (not more deadly) than the news will report.

 

 

 

 

 

I bet by the time they have the H1N1 Swine flu vaccine (sometime in Oct),  then at that time more than half of the kids will have already had it.  The Government told the drug companies to produce more swine flu than regular seasonal flu.  So there is now a shortage and we are fast running out of flu shots and have limited nasal flumist.  (Get yours as soon as you can)  And by the time we have the swine flu vaccine in full swine, that type of flu will be on the down slope and the regular flu will be on the increase in Jan with less people immunized against it.  Remember the two flus are just as dangerous to the high risk patients.  The government is going to be out of sink on their timing of vaccines in my personal opinion... maybe I'm wrong but we shall see.

 

The virus is on most store cart handles, church pews, restaurants, and other public areas.  So sterilize your hands frequently.  Not as many adults are getting sick since they wash their hands better and do not put their hands in their mouth as much.

Dr. K


Opinion Sept 16, 2009:

I am now seeing 10 cases of swine flu a day.  Most are not very sick.  I am sure the news will come out and say how many thousands of kids are getting the flu.  Closing the schools last Spring just delayed the spread to now.  The CDC finally came out and said to only treat the high risk patients with Tamiflu.  I have preached that for years.  If we treat everyone with Tamiflu then the germ will become resistant.  There have been already a handful of resistant H1N1.  If it becomes resistant like the old flu did, then we will not have anything to help the kids with cancer or the pregnant moms.  So most likely we will not be treating your child.  Also the flu test misses 50%.  So if they act like the flu we will approach the child as if they have it without testing.  If the test is pos then they have the flu, and if neg then they probably still have the flu and the test does not change what we do.  We hope to have the swine flu vaccine by late Oct. Please come in if you are in the high risk group (See below for list) .

For more info.... see:

http://www.cdc.gov/h1n1flu/antiviral.htm

 http://www.dallascounty.org/department/hhservices/documents/DCHHS_Flu_Report_2009_2010_Week_35_Final.pdf   this has great graphs on the big increase in flu in this area and see how rare in these months of the  year.

 Here is the CDC chart of deaths in children and you can see there is an increase number because of the increase number of cases… not because it is more deadly.  This is the deaths out of 80 million children so still very rare. 

 

 

This graph shows the cases last Spring (in pink).   Just wait till you see the graph that includes this Fall.

 The death of the 11yr old girl that died this week was caused by a mean bacteria and she did not die of the flu itself.  Watch for secondary bacterial infections.  Any fever past the 5th day would be a signal and come in right away.

Roger Knapp MD


Sept 12, 2009

Again news and personal opinion

The vaccine for the H1N1 flu(swine) is close to production.  We will have it late Oct or Nov.  Studies show good antibodies after one shot and they may only recommend one shot instead of 2 shots like they were suggesting last month.  That makes sense to me.  You need two vaccines 1 month apart if it is the first year you get flu vaccines.  We will not know how much vaccine supplies we will have and what age or category will be given the vaccine.   Maybe we will be given enough vaccine to vaccinate everyone.  We shall let you know.

Many parents have asked should I give the H1N1 vaccine to my child?   It is recommended for all children to 18 yrs old.   Remember this flu is not more dangerous than past flu.   There will be more cases because no one is immune to it.   My recommendation: do this year what you usually do.  If you think it is a good idea to vaccinate your children to flu and you have been doing that for years, then vaccinate them to both flu viruses.   If you don’t usually want to vaccinate them in the years  past and you still think it is not for your child, then don’t vaccinate them for either flu. 

Don’t let the news media scare you on this thing.  Just use good hand sanitation all year.


August 09

Personal Opinion.  The news is making this out of proportion. It is a new strain and many people will not be immune to it.  So there
will be more cases this year but it is not more dangerous than previous years.  Ignore the news that scares you into watching their
programs.  We should not close schools so talk to your school districts and keep the schools open.  People are most contagious
the day before symptoms and can shed virus for 7 days.  Most will tell them to go back to school when no fever for 24 hours. 
They already exposed others when coming down with it.  Masks will not prevent you from catching it but ill people should wear
masks so they do not spread it easily.  We should not treat all people with Tamiflu and other meds.  They should be treated if in a
high risk group.  If your child had type A flu in May, June, July Aug then you are probably immune to H1N1 and the vaccine may not be necessary. 
Otherwise I do recommend the vaccine for the regular flu and for the swine H1N1 flu in everyone over 6 months.  They will be
separate shots.  The swine flu will not be available in the nasal drops and only in shot form.

36,000 adults die every year from the flu and approx 180 kids die every year... out of 100s of millions.  Most have other health issues.
Very kids will die that are otherwise healthy.  1/million.  We mostly worry about kids <2yr, lung problems, cancer, immune problems,
heart problems, and pregnant mothers. Also the family of small infants <6 months should get shots to avoid them getting it.


July 09

These are some excerpts from CDC recommendations for Swine H1N1 flu.  You will see that the main individuals who should be treated with flu meds like Tamaflu are those at high risk.  Not everyone with the flu should get it.  If everyone is treated, then the germ will become resistant like last year’s flu virus.  If it becomes resistant through over use, then we do not have medication to help those who are high risk. 

 Main CDC site: http://www.cdc.gov/h1n1flu/

 The novel influenza A (H1N1) virus is susceptible to both neuraminidase inhibitor antiviral medications zanamivir and oseltamivir. It is resistant to the adamantane antiviral medications, amantadine and rimantadine. Antiviral treatment with either oseltamivir or zanamivir is recommended for patients who are hospitalized or who are at higher risk for seasonal influenza complications. Rare sporadic cases of oseltamivir resistant novel influenza A (H1N1) viruses have been detected worldwide. Additional information on antiviral recommendations for treatment and chemoprophylaxis of novel influenza A (H1N1) infection is available at http://www.cdc.gov/h1n1flu/recommendations.htm

 See video of their recommendations.  http://www.youtube.com/watch?v=L8oyiT-oZ-I

 Antiviral Resistance
This novel (H1N1) influenza virus is sensitive (susceptible) to the neuraminidase inhibitor antiviral medications, zanamivir and oseltamivir. It is resistant to the adamantane antiviral medications, amantadine and rimantadine.

Antiviral Treatment for Novel (H1N1) Influenza
For antiviral treatment of novel influenza (H1N1) virus infection, either oseltamivir or zanamivir are recommended. Recommendations for use of antivirals may change as data on antiviral effectiveness, clinical spectrum of illness, adverse events from antiviral use, and antiviral susceptibility data become available.

Treatment is recommended for:
All hospitalized patients with confirmed, probable or suspected novel influenza (H1N1).
Patients who are at higher risk for seasonal influenza complications (see the following).

High-risk groups: A person who is at high-risk for complications of novel influenza (H1N1) virus infection is defined as the same for seasonal influenza at this time. As more epidemiologic and clinical data become available, these risk groups might be revised.

  1. Children younger than 5 years old. The risk for severe complications from seasonal influenza is highest among children younger than 2 years old.
  2. Adults 65 years of age and older.
  3. Persons with the following conditions:

Chronic pulmonary (including asthma), cardiovascular (except hypertension), renal, hepatic, hematological (including sickle cell disease), neurologic, neuromuscular, or metabolic disorders (including diabetes mellitus);

  1. Immunosuppression, including that caused by medications or by HIV;
  2. Pregnant women;
  3. Persons younger than 19 years of age who are receiving long-term aspirin therapy;
  4. Residents of nursing homes and other chronic-care facilities.

See: http://www.cdc.gov/h1n1flu/recommendations.htm

 Patients who contract the H1N1 virus infection, but who are not in a high-risk group have had a self-limited respiratory illness similar to typical seasonal influenza. For most of these patients, the benefits of using antivirals may be modest. (Studies show it only shortens the illness by approxamately 1 day).  Therefore, testing, treatment and chemoprophylaxis efforts should be directed primarily at persons who are hospitalized or at higher risk for influenza complications.

 Post exposure antiviral chemoprophylaxis (giving medication to prevent illness when exposed)  with either oseltamivir or zanamivir can be considered for the following:

1.  Close contacts of cases (confirmed, probable, or suspected) who are at high-risk for complications of influenza

2.  Health care personnel, public health workers, or first responders who have had a recognized, unprotected close contact exposure to a person with novel (H1N1) influenza virus infection (confirmed, probable, or suspected) during that person’s infectious period.

 Interesting graphs:

 

Realize most adults will not go in and get tested but will bring in their children.  That is why there are
high numbers of kids.

As you can see there were a lot more cases in 07-08 year.

More in 07-08

This is scary but remember most (but not all) of these are kids with other health issues.
This is out millions of children.  You can see the second peak of cases this summer.